Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Megacystis microcolon intestinal hypoperistalsis syndrome: late sequelae and possible pathogenesis.
[megacystis-microcolon-intestinal hypoperistalsis syndrome]
Megacystis
microcolon
intestinal
hypoperistalsis
syndrome
(
MMIHS
)
is
characterized
by
hypoperistalsis
in
the
presence
of
ganglion
cells
,
malrotation
,
microcolon
,
bladder
distension
,
and
female
predilection
.
We
draw
attention
to
the
long
-term
management
of
a
patient
with
MMIHS
and
propose
a
pathogenetic
mechanism
to
account
for
this
syndrome
.
We
propose
that
the
initial
event
in
the
pathogenesis
of
MMIHS
is
an
intramural
inflammatory
process
that
affects
the
gastrointestinal
and
urinary
tracts
.
This
leads
to
extensive
fibrosis
which
destroys
the
intestinal
neural
network
,
producing
hypoperistalsis
.
The
same
process
causes
neuromuscular
incoordination
in
the
bladder
wall
,
resulting
in
irregular
bladder
contractions
against
a
"
closed
sphincter
"
leading
to
bladder
distension
.
The
enlarged
bladder
then
interferes
with
the
rotation
of
the
intestine
causing
malrotation
.
Diseases
Validation
Diseases presenting
"intestinal hypoperistalsis syndrome"
symptom
megacystis-microcolon-intestinal hypoperistalsis syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom