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[Benign course of malignant atrophic papulosis (Köhlmeier-Degos disease): lack of vessel occlusion as good prognostic sign?].
[malignant atrophic papulosis]
Morbus
Köhlmeier-
Degos
is
a
rare
systemic
disease
characterized
by
pathognomonic
cutaneous
lesions
with
typical
histology
.
We
report
the
case
of
a
22
-
year
-old
woman
with
a
benign
course
of
this
disease
and
discuss
therapeutical
options
.
The
patient
presented
with
whitish
papules
on
neck
,
trunk
and
extremities
that
slowly
developed
within
seven
months
.
Examination
of
the
skin
revealed
about
20
papules
of
2
-
5
mm
size
.
The
lesions
were
partly
skin
-colored
,
partly
with
an
erythematous
rim
and
showed
a
central
porcelain-like
atrophy
.
Histology
showed
an
interface-
dermatitis
and
a
wedge-shaped
mucin
deposition
with
sclerosis
of
the
upper
reticular
dermis
.
Organ
manifestation
was
absent
.
The
patient
was
started
on
a
daily
therapy
of
300
mg
acetyl
salicylic
acid
.
Over
the
course
of
24
months
single
new
lesions
appeared
at
a
reduced
frequency
.
Apart
from
the
malignant
form
of
Morbus
Köhlmeier-
Degos
there
exists
a
benign
course
which
may
be
successfully
controlled
with
anti-
platelet
therapy
.
We
speculate
that
the
lack
of
vessel
occlusion
in
the
histology
could
be
a
hallmark
of
a
benign
form
of
this
rare
disease
.
Diseases
Validation
Diseases presenting
"single new lesions"
symptom
malignant atrophic papulosis
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