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A random Abstract
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Inefficacy of intravenous immunoglobulins and infliximab in Degos' disease.
[malignant atrophic papulosis]
We
report
the
case
of
a
60
-
year
-old
man
who
presented
with
sudden
visual
loss
,
a
history
of
postprandial
abdominal
pain
,
malabsorption
,
and
skin
lesions
typical
of
systemic
Degos
'
disease
.
Despite
anti-aggregants
and
prednisone
the
patient
's
status
did
not
improve
.
On
the
basis
of
the
hypothetical
dysimmune
origin
of
this
disease
,
we
attempted
treatment
with
intravenous
immunoglobulins
,
without
success
.
We
then
administered
infliximab
(
Remicade
)
,
but
2
months
after
the
third
injection
the
patient
developed
mesenteric
infarction
and
died
.
We
therefore
believe
that
both
intravenous
immunoglobulins
and
antiTNFalpha
are
ineffective
for
the
treatment
of
Degos
'
disease
.
Diseases
Validation
Diseases presenting
"a history of postprandial abdominal pain"
symptom
malignant atrophic papulosis
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