Rare Diseases Symptoms Automatic Extraction

Degos cutaneous disease with features of connective tissue disease.

[malignant atrophic papulosis]

A 30-year-old woman was referred on April 2002 for a plaque that involved the internal aspect of the right leg, an erythema nodosum-like lesion on the lower extremities, and periarthritis on her left ankle. Subsequently, the patient developed anular, atrophic, growing, porcelain-white papules, with a thin rim of erythema and telangiectases over her upper and lower extremities. Clinically and histologically, these lesions were the characteristics of Degos disease. Despite arthritis and myositis that required treatment, low level C3 and C4, positive antinuclear antibodies, and elevated anticardiolipin antibodies only once, in a follow-up of 6 years the patient never developed a specific connective tissue disease or other systemic involvement. In conclusion, because clinical and histological findings of Degos disease might mimic connective tissue diseases, rheumatologists must be aware that this reaction pattern can be seen in a wide clinical spectrum of diseases.

Diseases presenting "arthritis" symptom

  • acute rheumatic fever
  • child syndrome
  • congenital adrenal hyperplasia
  • cystinuria
  • familial hypocalciuric hypercalcemia
  • familial mediterranean fever
  • focal myositis
  • harlequin ichthyosis
  • homocystinuria without methylmalonic aciduria
  • inclusion body myositis
  • lamellar ichthyosis
  • malignant atrophic papulosis
  • pyomyositis
  • sneddon syndrome
  • trochlear dysplasia
  • typhoid
  • wiskott-aldrich syndrome

This symptom has already been validated