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Exacerbation and remission of pulmonary micronodules with lymphangioleiomyomatosis around the time of childbirth.
[lymphangioleiomyomatosis]
We
present
a
case
of
multifocal
micronodular
pneumocyte
hyperplasia
(
MMPH
)
,
lymphangiomyomatosis
(
LAM
)
and
angiomyolipoma
(
AML
)
in
a
33
-
year
-old
woman
with
tuberous
sclerosis
complex
referred
to
us
during
her
first
pregnancy
.
Computed
tomography
of
the
chest
showed
diffuse
micronodules
and
cysts
in
both
lungs
.
Compared
to
those
before
pregnancy
,
the
number
of
micronodules
increased
evidently
.
We
hypothesized
the
micronodules
in
both
lungs
were
either
LAM
,
MMPH
,
or
a
combination
of
the
two
.
Bilateral
renal
AML
also
intensified
.
About
one
month
after
childbirth
,
LAM
and
renal
AML
decreased
without
treatment
.
Therefore
,
we
observed
that
LAM
and
AML
were
affected
by
the
pregnancy
.
To
the
best
of
our
knowledge
,
this
is
the
first
case
report
regarding
the
reversible
alteration
of
LAM
without
treatment
.
