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[A case report of pulmonary aspergillosis in lung transplant recipient successfully treated with inhalation administration of liposomal amphotericin B].
[lymphangioleiomyomatosis]
We
report
a
case
of
pulmonary
aspergillosis
in
lung
transplant
recipient
who
was
successfully
treated
with
inhalation
administration
of
anti-fungal
agent
.
The
case
was
33
-
year
-old
female
.
Two
years
ago
,
she
had
received
lung
transplant
because
of
lymphangioleiomyomatosis
.
One
year
ago
,
she
had
diagnosed
of
pulmonary
aspergillosis
and
successfully
treated
with
micafungin
and
itraconazole
.
Then
she
had
been
continuous
administered
with
itraconazole
.
In
June
20
xx
,
she
had
nausea
and
vomiting
and
was
diagnosed
of
viral
enteritis
.
Although
abdominal
symptoms
were
relieved
,
ground
glass
opacity
was
discovered
in
her
right
lung
.
Bronchoscopic
examination
revealed
ulceration
of
bronchus
with
white
necrotic
substance
.
Laboratory
culture
test
demonstrated
Aspergillus
spp
.
Finally
she
was
diagnosed
of
recurrent
pulmonary
aspergillosis
.
First
,
she
was
treated
with
intravascular
administration
of
micafungin
.
Then
,
inhalation
administration
of
liposomal
amphotericin
B
was
changed
.
Ground
glass
opacity
and
bronchial
region
of
pulmonary
aspergillosis
was
improved
.
Thereafter
,
inhalation
of
amphotericin
B
was
continued
and
no
recurrence
of
pulmonary
aspergillosis
has
been
found
.
Inhalation
of
anti-fungal
agent
could
be
an
option
for
pulmonary
aspergillosis
.