Rare Diseases Symptoms Automatic Extraction

Locked in and out: a case of emerging basilar artery obstruction secondary to vertebral artery dissection thrombolysed with intravenous rt-PA.

[locked-in syndrome]

The authors present a case in which intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) potentially saved a young man from locked-in syndrome or life threatening consequences. The patient presented with acute stroke secondary to vertebral artery dissection and was treated with intravenous rt-PA. There were no post thrombolysis complications and the patient left hospital with mild neurological symptoms. Our report suggests that in cases of acute posterior circulation stroke due to arterial dissection, treatment with intravenous thrombolysis is safe, practicable and effective.

Diseases presenting "stroke" symptom

  • acute rheumatic fever
  • adrenomyeloneuropathy
  • alexander disease
  • alpha-thalassemia
  • cadasil
  • cohen syndrome
  • dedifferentiated liposarcoma
  • fabry disease
  • heparin-induced thrombocytopenia
  • hereditary cerebral hemorrhage with amyloidosis
  • homocystinuria without methylmalonic aciduria
  • hydrocephalus with stenosis of the aqueduct of sylvius
  • kallmann syndrome
  • locked-in syndrome
  • malignant atrophic papulosis
  • neuralgic amyotrophy
  • sneddon syndrome
  • thoracic outlet syndrome
  • werner syndrome
  • zellweger syndrome

This symptom has already been validated