Rare Diseases Symptoms Automatic Extraction
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A random Abstract
Our Project
Our Team
Classification of intended phoneme production from chronic intracortical microelectrode recordings in speech-motor cortex.
[locked-in syndrome]
We
conducted
a
neurophysiological
study
of
attempted
speech
production
in
a
paralyzed
human
volunteer
using
chronic
microelectrode
recordings
.
The
volunteer
suffers
from
locked-
in
syndrome
leaving
him
in
a
state
of
near-
total
paralysis
,
though
he
maintains
good
cognition
and
sensation
.
In
this
study
,
we
investigated
the
feasibility
of
supervised
classification
techniques
for
prediction
of
intended
phoneme
production
in
the
absence
of
any
overt
movements
including
speech
.
Such
classification
or
decoding
ability
has
the
potential
to
greatly
improve
the
quality-of-life
of
many
people
who
are
otherwise
unable
to
speak
by
providing
a
direct
communicative
link
to
the
general
community
.
We
examined
the
performance
of
three
classifiers
on
a
multi-class
discrimination
problem
in
which
the
items
were
38
American
English
phonemes
including
monophthong
and
diphthong
vowels
and
consonants
.
The
three
classifiers
differed
in
performance
,
but
averaged
between
16
and
21
%
overall
accuracy
(
chance-level
is
1
/
38
or
2
.
6
%
)
.
Further
,
the
distribution
of
phonemes
classified
statistically
above
chance
was
non-uniform
though
20
of
38
phonemes
were
classified
with
statistical
significance
for
all
three
classifiers
.
These
preliminary
results
suggest
supervised
classification
techniques
are
capable
of
performing
large
scale
multi-class
discrimination
for
attempted
speech
production
and
may
provide
the
basis
for
future
communication
prostheses
.