Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Coma and disorders of consciousness.
[locked-in syndrome]
Patients
in
coma
,
vegetative
state
/
unresponsive
wakefulness
syndrome
,
and
in
minimally
conscious
states
pose
medical
,
scientific
,
and
ethical
challenges
.
As
patients
with
disorders
of
consciousness
are
by
definition
unable
to
communicate
,
the
assessment
of
pain
,
quality
of
life
,
and
end-of-life
preferences
in
these
conditions
can
only
be
approached
by
adopting
a
third
-person
perspective
.
Surveys
of
healthcare
workers
'
attitudes
towards
pain
and
end
of
life
in
disorders
of
consciousness
shed
light
on
the
background
of
clinical
reality
,
where
no
standard
medical-legal
framework
is
widely
accepted
.
On
the
other
hand
,
patients
with
locked-
in
syndrome
,
who
are
severely
paralyzed
but
fully
conscious
,
can
inform
about
subjective
quality
of
life
in
serious
disability
and
help
us
to
understand
better
the
underlying
factors
influencing
happiness
in
disease
.
In
the
medico-legal
arena
,
such
ethical
issues
may
be
resolved
by
previously
drafted
advance
directives
and
,
when
absent
,
by
surrogate
representation
.
Lately
,
functional
medical
imaging
and
electrophysiology
provide
alternative
means
to
communicate
with
these
challenging
patients
and
will
potentially
mediate
to
extract
responses
of
medical-ethical
content
.
Eventually
,
the
clinical
translation
of
these
advanced
technologies
in
the
medical
routine
is
of
paramount
importance
for
the
promotion
of
medical
management
of
these
challenging
patients
.
Diseases
Validation
Diseases presenting
"coma"
symptom
child syndrome
esophageal carcinoma
homocystinuria without methylmalonic aciduria
locked-in syndrome
pleomorphic liposarcoma
scrub typhus
severe combined immunodeficiency
triple a syndrome
This symptom has already been validated