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Malignant phyllodes tumor of the breast with liposarcomatous differentiation and intraductal hyperplasia.
[liposarcoma]
Phyllodes
tumor
of
the
breast
is
a
biphasic
fibroepithelial
neoplasm
.
10
to
20
%
of
phyllodes
tumor
show
malignant
transformation
,
often
in
the
form
of
stroma
,
which
usually
shows
fibrosarcomatous
differentiation
and
rarely
heterologous
sarcomatous
elements
.
Liposarcomatous
differentiation
is
not
common
among
phyllodes
tumors
.
The
correct
diagnosis
of
heterologous
liposarcomatous
differentiation
in
a
malignant
PT
requires
identification
of
the
biphasic
component
of
the
tumor
.
We
reported
a
case
of
malignant
phyllodes
tumor
which
initially
transformed
into
liposarcoma
,
in
addition
to
a
very
rare
intraductal
hyperplasia
and
flat
epithelial
atypia
.
The
patient
was
a
75
-
year
-old
woman
,
with
a
lump
in
the
left
breast
without
axillary
lymphadenopathy
.
She
also
have
a
positive
family
history
of
breast
carcinoma
.
She
underwent
surgery
and
still
alive
and
disease
free
after
one
year
.
Diseases
Validation
Diseases presenting
"neoplasm"
symptom
adrenal incidentaloma
alexander disease
aromatase deficiency
carcinoma of the gallbladder
cholangiocarcinoma
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dentin dysplasia
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial hypocalciuric hypercalcemia
focal myositis
hodgkin lymphoma, classical
hydrocephalus with stenosis of the aqueduct of sylvius
junctional epidermolysis bullosa
kabuki syndrome
liposarcoma
lymphangioleiomyomatosis
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wolf-hirschhorn syndrome
This symptom has already been validated