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Prevalence of malignant soft tissue tumors in extremities: an epidemiological study in syria.
[liposarcoma]
Although
the
majority
of
soft
tissue
masses
are
benign
,
it
is
important
to
consider
malignancy
in
differential
diagnoses
.
Because
most
soft
tissue
sarcomas
present
as
a
painless
mass
,
clinicians
must
watch
for
signs
suggestive
of
malignancy
,
including
large
size
,
rapid
growth
,
and
site
deep
into
the
deep
fascia
.
The
purpose
of
this
study
was
to
determine
the
relative
prevalence
according
to
sex
and
age
,
site
of
tumor
,
skeletal
distribution
,
and
treatment
(
surgery
,
chemotherapy
and
radiotherapy
)
before
and
after
surgery
,
and
ascertain
the
relative
frequency
of
these
tumors
in
specific
anatomic
sites
and
age
groups
based
on
pathological
studies
.
A
total
of
308
patients
,
with
a
musculoskeletal
tumor
were
evaluated
retrospectively
.
All
of
the
patients
enrolled
into
this
study
were
referred
to
the
Beirouni
Hospital
of
Damascus
University
with
a
proven
diagnosis
of
malignant
soft
tissue
tumors
from
the
beginning
of
January
2008
until
the
end
of
2010
.
The
prevalence
of
the
malignant
soft
tissue
tumors
in
these
patients
was
analyzed
.
For
purposes
of
analysis
,
all
lesions
were
placed
in
1
of
9
categories
:
hand
and
wrist
,
forearm
,
humorous
(
arm
)
,
proximal
limb
girdle
(
axilla
and
shoulder
)
,
foot
and
ankle
,
thigh
,
hip
and
buttocks
region
,
trunk
,
and
other
lesions
.
Age
and
sex
also
were
recorded
.
MALIGNANT
TUMORS
CONSISTED
OF
SEVEN
DIAGNOSTIC
CATEGORIES
:
malignant
fibrous
histiocytoma
(
23
%
)
,
liposarcoma
(
22
%
)
,
rhabdomyosarcoma
(
9
%
)
,
leiomyosarcoma
(
8
%
)
,
malignant
schwannoma
(
5
%
)
,
dermatofibrosarcoma
protuberans
(
5
%
)
,
synovial
sarcoma
(
10
%
)
,
fibrosarcoma
(
13
%
)
,
extraskeletal
chondrosarcoma
(
1
%
)
,
and
extraskeletal
Ewing
sarcoma
(
4
%
)
.
Despite
the
multitude
of
pathologic
possibilities
,
most
malignant
soft
-tissue
tumors
are
classified
into
a
small
number
of
diagnoses
.
These
may
be
further
defined
when
the
site
of
the
lesion
and
the
age
of
the
patient
are
considered
.
Knowledge
of
tumor
prevalence
will
assist
radiologists
in
establishing
a
suitably
ordered
differential
diagnosis
when
a
soft
-tissue
tumor
has
a
nonspecific
radiologic
appearance
.
Diseases
Validation
Diseases presenting
"liposarcoma"
symptom
dedifferentiated liposarcoma
erdheim-chester disease
focal myositis
gm1 gangliosidosis
liposarcoma
pleomorphic liposarcoma
well-differentiated liposarcoma
This symptom has already been validated