Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Our Team
[Clinical manifestations of Legionella pneumonia in hematology patients].
[legionellosis]
To
detect
the
most
common
clinical
manifestations
of
Legionella
pneumonia
(
LP
)
in
immunocompromized
patients
.
Clinical
manifestations
,
the
results
of
investigation
of
bronchoalveolar
lavage
fluid
(
BALF
)
and
urine
,
and
the
data
of
lung
computed
tomography
(
CT
)
were
studied
in
patients
with
blood
system
diseases
and
acute
respiratory
failure
(
ARF
)
.
The
diagnosis
of
LP
was
verified
in
8
(
10
.
5
%
)
of
76
patients
with
blood
system
diseases
and
ARF
.
The
disease
manifested
as
fever
,
higher
concentrations
of
inflammatory
markers
(
procalcitonin
,
fibrinogen
)
,
ARF
,
hypoxemia
,
and
infiltrative
lung
injury
.
Six
of
the
8
patients
were
switched
to
mechanical
ventilation
.
Lung
CT
showed
no
pathognomonic
signs
.
Five
of
the
8
patients
were
observed
to
have
renal
dysfunction
.
The
diagnosis
of
LP
was
made
on
the
basis
of
the
results
of
BALF
examination
in
7
patients
and
urinary
antigen
detection
in
1
.
The
disease
was
caused
by
Legionella
pneumophila
serogroup
1
in
3
patients
and
by
L
.
pneumophila
of
other
serogroups
in
the
other
patients
.
Therapy
with
respiratory
fluoroquinolones
was
performed
in
5
patients
.
Three
patients
died
from
progressive
ARF
and
hypoxemia
.
BALF
results
were
obtained
after
their
death
and
therapy
for
legionellosis
was
not
initiated
.
The
incidence
of
LP
is
10
.
5
%
in
hematology
patients
.
The
clinical
manifestations
of
legionellosis
are
nonspecific
;
its
diagnosis
requires
bacteriological
and
/
or
serological
evidence
.
Due
to
the
high
risk
of
death
,
it
is
reasonable
to
preuse
respiratory
fluoroquinolones
or
macrolides
in
immunocompromized
patients
with
progressive
ARF
and
suspected
Legionella
pneumonia
before
diagnosis
.
Diseases
Validation
Diseases presenting
"pneumonia"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
allergic bronchopulmonary aspergillosis
alpha-thalassemia
classical phenylketonuria
cohen syndrome
congenital diaphragmatic hernia
heparin-induced thrombocytopenia
hydrocephalus with stenosis of the aqueduct of sylvius
junctional epidermolysis bullosa
lamellar ichthyosis
legionellosis
liposarcoma
lymphangioleiomyomatosis
monosomy 21
oculocutaneous albinism
omenn syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
scrub typhus
severe combined immunodeficiency
triple a syndrome
waldenström macroglobulinemia
wiskott-aldrich syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
This symptom has already been validated