Junctional epidermolysis bullosa in a calf.

[junctional epidermolysis bullosa]

A case of epidermolysis bullosa in a calf descendent from a Gir bull and a Gir crossbreed cow is reported . The calf presented with exungulation of all hooves , widespread erosions and crusts on the skin , and ulcers in the oral cavity . Histologically , the skin showed subepidermal separation with clefts occasionally filled with eosinophilic clear fluid , cellular debris , or neutrophils . Ultrastructurally , there was epidermal-dermal separation at the level of the lamina lucida , with the lamina densa attached to the papillary dermis . The hemidesmosomes were poorly defined and small . The clinical , histological , and ultrastructural findings are characteristic of junctional epidermolysis bullosa .

Diseases
Validation

Diseases presenting "oral cavity" symptom

cowden syndrome

dedifferentiated liposarcoma

dentinogenesis imperfecta

dystrophic epidermolysis bullosa

epidermolysis bullosa simplex

junctional epidermolysis bullosa

kabuki syndrome

kindler syndrome

lamellar ichthyosis

oral submucous fibrosis

papillon-lefèvre syndrome

pleomorphic liposarcoma

proteus syndrome

sneddon syndrome

well-differentiated liposarcoma

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