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Mercury chronic toxicity might be associated to some cases of hydrocephalus in adult humans?
[hydrocephalus with stenosis of the aqueduct of sylvius]
Mercury
accumulates
in
nervous
tissue
causing
neurological
and
psychiatric
manifestations
.
Numerous
clinical
findings
have
been
described
in
patients
that
suffered
chronic
mercury
intoxication
.
Some
findings
,
such
as
hydrocephalus
,
have
been
described
only
in
experimental
studies
.
Following
,
we
present
a
case
of
50
year
-old
man
with
a
3
-
month
history
of
severe
frontal
headache
episodes
and
vision
loss
together
with
a
history
of
asthenia
,
anorexia
,
muscle
pain
,
fatigue
and
neuropsychiatric
symptoms
.
The
magnetic
resonance
imaging
showed
hydrocephalus
and
stenosis
of
aqueduct
of
Sylvius
.
This
patient
reported
that
he
worked
as
laboratory
metallurgic
auxiliary
for
over
30
years
.
During
this
time
,
he
had
been
chronically
exposed
to
elemental
mercury
.
The
metals
whole
blood
test
was
normal
,
except
by
his
blood
mercury
level
that
was
61
.
5
μg
/
L
(
normal
~
1
μg
/
L
)
.
In
our
best
knowledge
,
hydrocephalus
and
stenosis
of
aqueduct
of
Sylvius
have
been
described
only
in
animals
exposed
to
methylmercury
during
their
gestation
.
We
think
that
this
case
of
hydrocephalus
might
be
associated
with
the
chronic
mercury
exposure
and
therefore
this
etiology
must
be
taken
in
account
in
a
patient
with
hydrocephalus
of
unknown
etiology
.
Diseases
Validation
Diseases presenting
"blood mercury level"
symptom
hydrocephalus with stenosis of the aqueduct of sylvius
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