Tetralogy of Fallot with Holt-Oram syndrome.

[holt-oram syndrome]

Holt-Oram syndrome (HOS ) is characterised by mild to severe congenital cardiac defects and skeletal abnormalities of the upper limb . This syndrome is also referred to as Hand -Heart syndrome . The most common cardiac disorder is an ostium secundum detected an atrial septal defect (ASD ), followed by ventricular septal defect (VSD ) and ostium primum ASD . We report a case of HOS with tetralogy of Fallot (TOF ). This association is very rare and is hardly reported in the literature .