Holt-Oram syndrome with aortopulmonary window--a rare association.

[holt-oram syndrome]

A 4 -month -old male infant presented with recurrent cough for 2 months . He had a shortened right upper limb with absent right thumb and continuous murmur in the left parasternal area . The X-ray showed an absent radius and the first metacarpal and phalyngeal bones on the right side . Echocardiogram revealed aortopulmonary window and small secundum atrial septal defect . Aortopulmonary window was successfully treated by device closure . Holt-Oram syndrome with aortopulmonary window is an extremely rare association .