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The prognostic value of interim positron emission tomography scan in patients with classical Hodgkin lymphoma.
[hodgkin lymphoma, classical]
The
prognostic
value
of
interim
positron
emission
tomography
(
PET
)
was
evaluated
after
2
cycles
of
doxorubicin
,
bleomycin
,
vinblastin
and
dacarbazine
in
classical
Hodgkin
lymphoma
patients
(
n
=
229
)
,
based
on
Deauville
criteria
.
In
early
stage
non-bulky
disease
,
bulky
stage
II
disease
,
advanced
stage
low
International
Prognostic
Score
(
IPS
≤
2
)
and
advanced
stage
(
IPS
≥
3
)
,
3
-
year
progression-free
survival
rates
in
PET
2
-
negative
vs
.
PET
2
-
positive
groups
were
95
·
9
%
vs
.
76
·
9
%
(
P
<
0
·
0018
)
,
83
·
3
%
vs
.
20
·
0
%
(
P
=
0
·
017
)
,
77
·
0
%
vs
.
30
·
0
%
(
P
<
0
·
001
)
and
71
·
0
%
vs
.
44
·
4
%
(
P
=
0
·
155
)
,
respectively
.
The
outcome
after
positive
PET
2
was
better
than
previously
reported
.
The
results
from
non-randomized
studies
of
PET
2
-
guided
therapy
would
be
valuable
with
careful
interpretation
.
Diseases
Validation
Diseases presenting
"early stage"
symptom
adrenomyeloneuropathy
allergic bronchopulmonary aspergillosis
aromatase deficiency
cadasil
carcinoma of the gallbladder
child syndrome
cholangiocarcinoma
congenital adrenal hyperplasia
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
harlequin ichthyosis
hereditary cerebral hemorrhage with amyloidosis
hodgkin lymphoma, classical
kindler syndrome
lymphangioleiomyomatosis
neonatal adrenoleukodystrophy
pyomyositis
scrub typhus
sneddon syndrome
typhoid
von hippel-lindau disease
zellweger syndrome
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