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Estimated radiation exposure and cancer risk from CT and PET/CT scans in patients with lymphoma.
[hodgkin lymphoma, classical]
The
purpose
of
this
study
was
to
estimate
total
effective
dose
and
cancer
risk
related
to
treatment
monitoring
and
surveillance
computed
tomography
(
CT
)
scans
in
a
cohort
of
patients
diagnosed
with
lymphoma
.
76
patients
with
head
,
neck
,
chest
,
abdomen
or
pelvis
CT
and
whole-body
positron
emission
tomography
(
PET
)
/
CT
were
identified
from
an
institutional
lymphoma
database
;
this
included
54
(
71
%
)
patients
with
non-
Hodgkin
and
22
(
29
%
)
patients
with
classical
Hodgkin
lymphoma
.
Average
treatment
and
surveillance
periods
were
8
months
(
range
,
3
-
14
mo
)
and
23
months
(
range
,
1
-
40
mo
)
,
respectively
.
Radiation
exposure
was
estimated
from
the
dose-length
product
(
DLP
)
for
CT
scans
and
milli-
Curies
and
DLP
for
PET
/
CT
scans
.
Cancer
risk
was
estimated
using
the
Biological
Effects
of
Ionizing
Radiation
model
.
During
their
treatment
period
,
45
patients
had
161
CT
exams
and
39
patients
had
73
PET
/
CT
exams
.
Mean
effective
dose
was
39
.
3
mSv
(
range
,
7
.
1
-
100
mSv
)
.
During
the
surveillance
period
,
60
patients
had
378
CT
exams
and
25
patients
had
39
PET
/
CT
exams
.
Mean
effective
dose
was
53
.
2
mSv
(
range
,
2
.
6
-
154
mSv
)
.
Seventeen
of
76
(
22
.
4
%
)
patients
had
total
cumulative
doses
greater
than
100
mSv
.
The
mean
increase
in
estimated
cancer
risk
was
0
.
40
%
;
the
greatest
estimated
risk
to
any
one
patient
was
1
.
19
%
.
Mean
total
effective
dose
and
mean
estimated
cancer
risk
were
low
in
patients
with
lymphoma
undergoing
serial
imaging
,
suggesting
that
theoretical
risks
of
radiation-induced
cancer
need
not
be
a
major
consideration
in
radiologic
follow-up
.
Diseases
Validation
Diseases presenting
"estimated cancer risk was 0.40%"
symptom
hodgkin lymphoma, classical
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