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[The endotoxine aggression in the pathogenesis of postoperative complications in children with Hirsprung disease].
[hirschsprung disease]
Signs
of
disseminated
intravascular
clotting
(
DIC
)
,
which
were
considered
the
laboratory
sign
of
the
subcompensated
endotoxine
aggression
,
were
detected
in
20
children
with
the
Hirsprung
disease
,
aged
3
months
-
11
years
.
Under
the
influence
of
the
operation
stress
the
subcompensated
DIC
transformed
to
the
acute
decompensated
reaction
,
which
led
to
early
complications
,
such
as
anastomosistis
with
tendency
to
the
insufficiency
or
stenosis
,
enterocolitis
,
etc
.
The
study
revealed
not
only
the
straight
connection
between
the
postoperative
complications
and
endotoxine
aggression
,
but
the
necessity
of
preoperative
preparation
,
directed
on
the
decrease
of
the
intestinal
endotoxin
level
and
normalization
of
antiendotoxin
immunity
.
Diseases
Validation
Diseases presenting
"but the necessity of preoperative preparation"
symptom
hirschsprung disease
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