Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Peristeen integrated transanal irrigation system successfully treats faecal incontinence in children.
[hirschsprung disease]
Faecal
incontinence
secondary
to
myelomeningocele
,
Hirschsprung
disease
,
and
anorectal
anomalies
remains
a
significant
and
common
problem
.
We
aimed
to
report
our
5
-
year
experience
with
the
Peristeen
trans-
anal
irrigation
system
(
TAIS
)
to
manage
such
children
.
This
study
was
a
combination
of
a
retrospective
case
note
review
and
assessment
using
a
validated
quality
of
life
questionnaire
(
QOL
)
to
determine
pre-
and
post-
TAIS
bowel
function
and
continence
.
QOL
scores
and
functional
outcomes
before
and
during
TAIS
use
were
compared
using
Wilcoxon
matched
pairs
test
(
p
<
0
.
05
significant
)
.
Twenty
-
four
children
(
median
age
6
years
)
were
managed
with
the
TAIS
2006
-
2011
to
treat
faecal
incontinence
.
Three
did
not
tolerate
the
system
.
Median
QOL
scores
in
20
out
of
21
patients
using
TAIS
demonstrated
significant
improvement
in
bowel
management
and
continence
.
Two
discontinued
use
due
to
failure
to
improve
continence
;
one
underwent
the
Malone
antegrade
continence
enema
(
MACE
)
procedure
and
one
returned
to
oral
/
rectal
medications
.
Nineteen
of
24
patients
(
79
%
)
continue
to
use
TAIS
.
The
Peristeen
TAIS
is
an
effective
,
safe
,
non-operative
alternative
to
MACE
in
children
with
faecal
incontinence
,
if
initial
compliance
can
be
achieved
.
