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Development of Frequency of Stools over Time in Children with Hirschsprung Disease Posttransanal Endorectal One-Stage Pull-through.
[hirschsprung disease]
Background
The
transanal
endorectal
one
-
stage
pull-through
(
TERPT
)
procedure
in
children
with
Hirschsprung
disease
(
HD
)
is
frequently
used
worldwide
.
To
give
the
children
's
families
realistic
expectations
and
to
plan
the
medical
care
for
the
period
after
TERPT
,
the
outcome
is
of
great
importance
.
Aim
The
aim
of
this
article
is
to
collect
information
on
the
number
of
stools
passed
daily
after
one
-
stage
TERPT
procedure
for
HD
.
Patients
and
Methods
A
prospective
follow-up
study
for
collecting
information
on
the
outcome
of
planned
TERPT
from
2005
through
2012
was
performed
.
A
control
group
consisting
of
age
and
gender
matched
children
was
used
.
Results
The
results
show
an
initial
high
frequency
of
daily
stools
,
median
12
stools
/
day
(
range
,
3
-
30
stools
/
day
)
,
reaching
an
acceptable
situation
with
median
4
stools
/
day
(
range
,
0
-
10
stools
/
day
)
after
1
year
.
After
4
years
,
the
number
of
stools
did
not
differ
significantly
from
healthy
controls
.
Conclusion
This
study
shows
that
it
takes
4
years
after
TERPT
before
the
number
of
stools
becomes
normalized
.
To
compare
the
long
-term
outcome
,
it
would
be
desirable
to
have
uniform
regular
reports
on
the
daily
frequency
of
passed
stools
,
incontinence
,
and
constipation
during
the
years
after
TERPT
.
Diseases
Validation
Diseases presenting
"long-term outcome"
symptom
aniridia
cholangiocarcinoma
classical phenylketonuria
cystinuria
erythropoietic protoporphyria
esophageal squamous cell carcinoma
fabry disease
hirschsprung disease
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
inclusion body myositis
kabuki syndrome
krabbe disease
oligodontia
papillon-lefèvre syndrome
primary hyperoxaluria type 1
trochlear dysplasia
von hippel-lindau disease
waldenström macroglobulinemia
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