Successful use of fondaparinux in a patient with heparin-induced thrombocytopenia while on extracorporeal membrane oxygenation after mitral valve redo surgery.

[heparin-induced thrombocytopenia]

In patients with respiratory failure and impairment of the left ventricle , arteriovenous extracorporeal membrane oxygenation (ECMO ) offers further therapeutic options . Systemic anticoagulation is mandatory and heparin is routinely administrated . However , repeated exposure to heparin may cause heparin-induced thrombocytopenia (HIT ) and carries a risk of thrombotic mortality and morbidity . We present a patient who developed HIT during ECMO support and was treated successfully and safely by fondaparinux . Fondaparinux can be used for thromboembolic treatment or prophylaxis in a patient with HIT .

Diseases
Validation

Diseases presenting "respiratory failure" symptom

achondroplasia

allergic bronchopulmonary aspergillosis

congenital diaphragmatic hernia

familial hypocalciuric hypercalcemia

gm1 gangliosidosis

harlequin ichthyosis

heparin-induced thrombocytopenia

inclusion body myositis

junctional epidermolysis bullosa

lamellar ichthyosis

legionellosis

lymphangioleiomyomatosis

proteus syndrome

pyruvate dehydrogenase deficiency

typhoid

von hippel-lindau disease

This symptom has already been validated