Harlequin ichthyosis in a HanWoo calf.

[harlequin ichthyosis]

Ichthyosis (fish scale disease ) is a rare hereditary disease and characterized by excessive cutaneous scale formation . A male HanWoo calf born by natural service was found with fissures and thickened , scaly , cutaneous plates covering over 90 % of its body . Histopathological feature was excess compact orthokeratotic hyperkeratosis involving surface of the epidermis and follicular epithelia . The calf had small malformed ears , ectropion , eclabium and an abnormal nose . Gross and histopathologic findings in calf were consistent with those of harlequin ichthyosis , and it was the first observed harlequin ichthyosis in HanWoo cattle .