Harlequin ichthyosis in a neonate born with assisted reproductive technology: a case report.

[harlequin ichthyosis]

Harlequin ichthyosis is a rare and the most severe form of congenital ichthyosis . Although prenatal diagnosis isdifficult for this disorder , recently , this obstacle has markedly improved with the use of DNA-based prenataldiagnosis . Here in , we presented a neonate with harlequin ichthyosis born by assisted reproductive technology (ART ). In this case , the diagnosis of harlequin ichthyosis was not established by conventional prenatal screening .