Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Assessment of sleep problems in children with familial Mediterranean fever.
[familial mediterranean fever]
This
study
aimed
to
investigate
sleep
patterns
,
sleep
disturbances
and
possible
factors
that
are
associated
with
sleep
disturbances
among
children
with
familial
Mediterranean
fever
(
FMF
)
.
Fifty
-
one
patients
with
FMF
and
84
age-
and
sex-matched
healthy
controls
were
enrolled
in
the
study
.
The
patients
who
had
an
attack
during
the
last
2
weeks
were
not
included
.
Demographic
data
,
FMF
symptoms
,
disease
duration
,
dose
of
colchicine
,
disease
severity
score
,
number
of
attacks
in
the
last
year
,
MEFV
mutation
and
serum
C-
reactive
protein
(
CRP
)
levels
were
recorded
for
each
patient
.
A
Children
's
Sleep
Habits
Questionnaire
was
performed
.
The
total
sleep
scores
of
the
patients
with
FMF
were
significantly
higher
than
the
control
group
.
Total
sleep
durations
were
similar
between
FMF
patients
and
controls
.
Children
with
FMF
had
significantly
higher
scores
regarding
sleep
-onset
delay
,
sleep
anxiety
,
night
wakings
and
sleep
-disordered
breathing
when
compared
to
healthy
controls
.
There
was
a
significant
positive
correlation
between
number
of
attacks
in
the
last
year
and
sleep
onset
delay
,
night
wakings
and
sleep
disordered-breathing
.
Disease
severity
score
and
CRP
levels
were
not
associated
with
any
of
the
subscale
scores
.
The
patients
with
exertional
leg
pain
had
significantly
higher
total
sleep
scores
than
the
ones
without
.
Furthermore
,
patients
with
exertional
leg
pain
had
significantly
higher
subscale
scores
regarding
sleep
onset
delay
,
parasomnias
and
sleep
-disordered
breathing
.
This
study
showed
for
the
first
time
that
children
with
FMF
had
more
sleep
disturbances
than
their
healthy
peers
.
Higher
numbers
of
attacks
and
exertional
leg
pain
were
associated
with
poor
sleep
quality
.
In
conclusion
,
this
study
underlines
the
need
to
assess
and
manage
sleep
problems
in
children
with
FMF
.
Diseases
Validation
Diseases presenting
"significant positive correlation"
symptom
acute rheumatic fever
congenital adrenal hyperplasia
familial mediterranean fever
kallmann syndrome
trochlear dysplasia
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom