Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Neutrophil-Lymphocyte Ratio in Patients With Familial Mediterranean Fever.
[familial mediterranean fever]
Blood
neutrophil-
to
-lymphocyte
(
N
/
L
)
ratio
is
an
indicator
of
the
overall
inflammatory
status
of
the
body
,
and
an
alteration
in
N
/
L
ratio
may
be
found
in
patients
with
familial
Mediterranean
fever
(
FMF
)
.
The
aim
of
this
study
was
to
investigate
the
interrelationship
between
N
/
L
ratio
and
FMF
.
O
ne
hundred
and
fifteen
patients
and
controls
were
enrolled
in
the
study
.
The
cases
in
the
study
were
categorized
as
FMF
with
attack
,
FMF
with
attack-free
period
,
and
controls
.
The
neutrophil
and
lymphocyte
counts
were
recorded
,
and
the
N
/
L
ratio
was
calculated
from
these
parameters
.
All
patients
were
diagnosed
according
to
Tel
Hashomer
criteria
.
A
total
of
79
FMF
patients
were
included
in
the
study
and
all
subjects
were
receiving
colchicine
treatment
at
the
time
.
The
serum
N
/
L
ratios
of
active
patients
were
significantly
higher
than
those
of
attack-free
FMF
patients
and
controls
(
P
<
0
.
001
)
.
The
optimum
N
/
L
ratio
cut-off
point
for
active
FMF
was
2
.
63
with
sensitivity
,
specificity
,
positive
predictive
value
,
and
negative
predictive
value
of
0
.
62
(
0
.
41
-
0
.
80
)
,
0
.
85
(
0
.
72
-
0
.
93
)
,
0
.
67
(
0
.
44
-
0
.
85
)
,
and
0
.
82
(
0
.
69
-
0
.
91
)
,
respectively
.
The
overall
accuracy
of
the
N
/
L
ratio
in
determination
of
FMF
patients
during
attack
was
71
%
.
Our
results
demonstrate
that
N
/
L
ratio
is
higher
in
patients
with
active
FMF
compared
with
FMF
patients
in
remission
and
controls
,
and
a
cut-off
value
of
2
.
63
can
be
used
to
identify
patients
with
active
FMF
.
Diseases
Validation
Diseases presenting
"overall inflammatory status of the body"
symptom
familial mediterranean fever
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom