The impact of familial Mediterranean fever on reproductive system.

[familial mediterranean fever]

Familial Mediterranean fever (FMF ) is an autosomal recessive disease characterized by recurrent attacks of fever , peritonitis , pleuritis , arthritis , or erysipelas -like skin lesion . FMF is the most common periodic febrile syndrome affecting more than 150 ,000 people worldwide . The majority of patients develop FMF before the age of 20 . FMF may cause amyloidosis , which mainly affects the kidneys but may also be accumulated in other organs such as the heart , gastrointestinal tract , and reproductive organs . FMF being a systemic disorder with a risk for amyloidosis , affecting patients in their childbearing years , and with its lifelong colchicine therapy raises concern about its effect on the reproductive system . In this article , we review the impact of FMF and its treatment to the reproductive system of male and female patients , pregnancy , and lactation .

Diseases
Validation

Diseases presenting "female patients" symptom

adrenomyeloneuropathy

aromatase deficiency

benign recurrent intrahepatic cholestasis

carcinoma of the gallbladder

classical phenylketonuria

congenital adrenal hyperplasia

cushing syndrome

erdheim-chester disease

esophageal adenocarcinoma

esophageal carcinoma

esophageal squamous cell carcinoma

fabry disease

familial hypocalciuric hypercalcemia

familial mediterranean fever

heparin-induced thrombocytopenia

lymphangioleiomyomatosis

oligodontia

papillon-lefèvre syndrome

phenylketonuria

pyruvate dehydrogenase deficiency

sneddon syndrome

trochlear dysplasia

von hippel-lindau disease

wolf-hirschhorn syndrome

x-linked adrenoleukodystrophy

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