Three patients with familial Mediterranean fever: a possible underdiagnosed entity in Japan.

[familial mediterranean fever]

Familial Mediterranean fever (FMF ) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation . FMF is mostly reported in the Mediterranean region and is considered to be rare in Japan with estimated 292 cases . We treated three unrelated FMF patients in one year in a city with 144 ,000 residents . Two of the three patients were over 70 years old . FMF may therefore be underdiagnosed in Japan .

Diseases
Validation

Diseases presenting "fever" symptom

22q11.2 deletion syndrome

acute rheumatic fever

alexander disease

allergic bronchopulmonary aspergillosis

canavan disease

carcinoma of the gallbladder

child syndrome

congenital toxoplasmosis

cushing syndrome

cystinuria

dracunculiasis

erdheim-chester disease

esophageal adenocarcinoma

esophageal carcinoma

familial mediterranean fever

focal myositis

hodgkin lymphoma, classical

lamellar ichthyosis

legionellosis

locked-in syndrome

malignant atrophic papulosis

neonatal adrenoleukodystrophy

neuralgic amyotrophy

oculocutaneous albinism

papillon-lefèvre syndrome

pyomyositis

pyruvate dehydrogenase deficiency

scrub typhus

severe combined immunodeficiency

sneddon syndrome

systemic capillary leak syndrome

triple a syndrome

typhoid

waldenström macroglobulinemia

wolf-hirschhorn syndrome

This symptom has already been validated