Intrauterine device may trigger typical attacks of familial Mediterranean fever: a case report.

[familial mediterranean fever]

Familial Mediterranean fever (FMF ) is an autosomal recessive disorder characterized by episodic , recurrent , self-limited attacks of fever and serositis (sterile peritonitis , pleuritis , arthritis , etc ). The insufficiency in restriction of mild inflammation contributes this consequence in FMF .Intrauterine devices (IUDs ) have been widely used in the world for contraception by gynecologists as an effective and safe method . Herein , we present a woman with FMF as the first case , whose attacks were triggered by copper-containing IUD . Our hypothesis in the present case was that sterile mild inflammation in the uterus caused by copper-containing IUD may be the initial source of systemic inflammatory response .In our opinion , clinicians should consider that the copper-containing IUDs may be another cause of FMF attacks in women using this contraceptive method .

Diseases
Validation

Diseases presenting "fever" symptom

22q11.2 deletion syndrome

acute rheumatic fever

alexander disease

allergic bronchopulmonary aspergillosis

canavan disease

carcinoma of the gallbladder

child syndrome

congenital toxoplasmosis

cushing syndrome

cystinuria

dracunculiasis

erdheim-chester disease

esophageal adenocarcinoma

esophageal carcinoma

familial mediterranean fever

focal myositis

hodgkin lymphoma, classical

lamellar ichthyosis

legionellosis

locked-in syndrome

malignant atrophic papulosis

neonatal adrenoleukodystrophy

neuralgic amyotrophy

oculocutaneous albinism

papillon-lefèvre syndrome

pyomyositis

pyruvate dehydrogenase deficiency

scrub typhus

severe combined immunodeficiency

sneddon syndrome

systemic capillary leak syndrome

triple a syndrome

typhoid

waldenström macroglobulinemia

wolf-hirschhorn syndrome

This symptom has already been validated