Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Relationship between TLR4 and NF-κB p65 protein expressions and clinical radiosensitivity of patients with esophageal squamous cell carcinoma.
[esophageal squamous cell carcinoma]
To
study
the
relationship
between
TLR
4
and
NF-κB
p
65
protein
expressions
in
tumor
tissues
after
radiotherapy
and
clinical
radiosensitivity
of
patients
with
esophageal
squamous
cell
carcinoma
.
A
total
of
93
patients
with
esophageal
squamous
cell
carcinoma
first
treated
in
our
hospital
by
radiotherapy
and
surgeries
from
November
2010
to
December
2013
were
selected
.
They
were
then
divided
into
a
severe
reaction
group
,
a
moderate
reaction
group
and
a
mild
reaction
group
according
to
the
postoperative
pathological
examination
results
of
tumor
tissues
.
The
expressions
of
TLR
4
and
NF-κB
p
65
in
the
tumor
samples
were
detected
by
Western
blotting
.
Compared
with
the
severe
reaction
group
,
the
expression
levels
of
TLR
4
and
NF-κB
p
65
in
the
moderate
reaction
group
significantly
increased
(
P
<
0
.
05
)
.
Similarly
,
the
expression
levels
of
the
mild
reaction
group
were
significantly
higher
than
those
of
the
moderate
reaction
group
(
P
<
0
.
05
)
.
Reducing
the
expression
levels
of
TLR
4
and
NF-κB
p
65
proteins
may
increase
the
radiosensitivity
of
patients
with
esophageal
cancer
.
Diseases
Validation
Diseases presenting
"squamous cell carcinoma"
symptom
carcinoma of the gallbladder
child syndrome
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
junctional epidermolysis bullosa
kallmann syndrome
kindler syndrome
liposarcoma
monosomy 21
oculocutaneous albinism
oral submucous fibrosis
papillon-lefèvre syndrome
This symptom has already been validated