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Our Project
Our Team
[Analysis of early lymph node metastasis pattern and prognosis in thoracic esophageal squamous cell carcinoma].
[esophageal squamous cell carcinoma]
To
investigate
the
pattern
of
early
lymph
node
metastasis
of
thoracic
esophageal
squamous
cell
carcinoma
and
its
prognostic
value
.
Clinical
and
follow-up
data
of
126
patients
with
pathological
stage
pN
1
of
esophageal
squamous
cell
carcinoma
undergoing
radical
esophagectomy
in
our
department
from
January
2005
to
December
2008
were
analyzed
retrospectively
.
Impact
of
lymph
node
metastasis
pattern
on
prognosis
was
investigated
.
The
relatively
common
sites
of
lymph
node
metastasis
were
upper
mediastinum
(
53
.
8
%
)
,
middle
and
lower
thoracic
paraesophageal
(
38
.
3
%
)
,
right
and
left
cardiac
(
34
.
4
%
)
and
the
left
gastric
artery
(
36
.
8
%
)
.
Univariate
analysis
showed
that
the
lymph
node
metastasis
of
subcarinal
,
middle
and
lower
thoracic
paraesophageal
and
the
left
gastric
artery
was
associated
with
5
-
year
survival
rate
.
Multivariate
analysis
revealed
that
the
presence
of
subcarinal
and
middle
and
lower
thoracic
paraesophagea
lymph
node
metastasis
was
an
independent
risk
factor
of
survival
.
Upper
mediastinal
,
middle
and
lower
thoracic
paraesophageal
,
right
and
left
cardiac
and
the
left
gastric
artery
are
the
earliest
lymph
node
metastasis
sites
of
esophageal
squamous
cell
carcinoma
.
The
presence
of
subcarinal
and
middle
and
lower
thoracic
paraesophagea
lymph
node
metastasis
is
an
independent
risk
factor
of
survival
.
Patient
prognosis
should
be
analyzed
with
lymph
node
metastasis
pattern
based
on
the
7
th
edition
UICC-AJCC
TNM
classification
system
.
Diseases
Validation
Diseases presenting
"early lymph node metastasis"
symptom
esophageal squamous cell carcinoma
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