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Clinical outcome of photodynamic therapy in esophageal squamous cell carcinoma.
[esophageal squamous cell carcinoma]
The
aim
of
this
study
was
to
evaluate
the
feasibility
and
safety
of
photodynamic
therapy
(
PDT
)
as
a
curative
treatment
option
or
as
palliative
therapy
for
esophageal
squamous
cell
carcinoma
.
Medical
records
of
patients
who
received
PDT
for
esophageal
squamous
cell
carcinoma
,
including
carcinoma
in
situ
,
were
reviewed
retrospectively
.
Survival
analysis
was
performed
using
the
Kaplan-
Meier
method
.
A
total
of
31
cases
were
treated
with
PDT
between
2003
and
2013
.
Treatment
was
for
palliative
purposes
in
11
cases
(
35
.
5
%
)
and
for
therapeutic
purposes
in
20
cases
(
64
.
5
%
)
.
We
achieved
15
cases
(
48
.
4
%
)
of
complete
remission
and
16
(
51
.
6
%
)
cases
of
partial
remission
during
the
follow-up
period
.
There
were
6
fatalities
,
5
of
which
were
related
to
disease
progression
.
Complications
,
including
benign
strictures
,
occurred
in
11
cases
(
35
.
5
%
)
but
there
was
only
1
complication-related
death
.
Recurrence
occurred
in
2
patients
with
complete
remission
.
Overall
survival
was
31
.
9
months
for
patients
with
complete
remission
and
28
.
2
months
for
those
with
partial
remission
.
Disease-free
survival
of
patients
with
complete
remission
was
21
.
9
months
.
Our
data
suggest
that
photodynamic
therapy
is
a
reasonable
palliative
treatment
option
with
acceptable
complication
rates
for
esophageal
cancer
and
could
be
performed
for
therapeutic
purposes
in
cases
of
early
esophageal
cancer
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated
