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Association between Dietary Behavior and Esophageal Squamous Cell Carcinoma in Yanting.
[esophageal squamous cell carcinoma]
Yanting
is
one
of
high
risk
areas
for
esophageal
cancer
and
the
screening
program
was
therefore
initiated
there
.
This
study
was
aimed
to
investigate
the
dietary
behaviors
on
the
risk
of
esophageal
squamous
cell
carcinoma
(
ESCC
)
,
among
the
individuals
with
normal
and
abnormal
esophagus
mucosa
.
A
frequency
matched
case-controls
study
was
proposed
to
estimate
the
different
distribution
of
dietary
behavior
between
individuals
of
control
,
esophagitis
and
cancer
groups
.
Cancer
cases
were
selected
from
hospitals
.
Esophagitis
cases
and
controls
were
selected
from
screening
population
for
ESCC
.
Health
workers
collected
data
for
1
year
prior
to
interview
,
in
terms
of
length
of
finishing
a
meal
,
temperature
of
eaten
food
and
interval
between
water
boiling
and
drinking
.
Chi
-square
,
Kruskal-
Wallis
tests
and
unconditional
logistic
regression
model
were
used
to
estimate
differences
and
associations
between
groups
.
Compared
with
controls
,
length
of
finishing
a
meal
≥
15
mins
was
related
to
a
reduced
OR
for
cancer
(
OR
=
0
.
46
,
95
%
CI
,
0
.
22
-
0
.
97
)
and
even
compared
with
cases
of
esophagitis
,
the
OR
of
cancer
was
reduced
to
0
.
30
(
95
%
CI
,
0
.
13
-
0
.
72
)
.
The
OR
for
often
eating
food
at
a
high
temperature
was
2
.
48
(
95
%
CI
1
.
06
,
5
.
82
)
for
ESCC
as
compared
with
controls
.
Interval
between
water
boiling
and
drinking
of
≥
10
mins
was
associated
with
lower
risk
of
cancer
:
the
OR
was
0
.
18
compared
with
controls
and
0
.
49
with
esophagitis
cases
(
p
<
0
.
05
)
.
Length
of
eating
food
≥
15
mins
and
interval
between
water
boiling
and
drinking
≥
10
mins
are
potentially
related
to
reduced
risk
of
esophageal
SCC
,
compared
with
individuals
with
normal
and
abnormal
esophageal
mucosa
.
Recommendations
to
Yanting
residents
to
change
their
dietary
behaviors
should
be
made
in
order
to
reduce
cancer
risk
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated