Rare Diseases Symptoms Automatic Extraction

Effect of physiological exercise on osteocalcin levels in subjects with adrenal incidentaloma.

[adrenal incidentaloma]

In the present study, we have evaluated whether physical exercise affect low osteocalcin concentrations observed in patients with subclinical hypercortisolism.Sixteen patients (10 men and 6 women, age 38-55 yr) with adrenal incidentaloma were studied. Fifteen healthy volunteers matched for age (range 35-47 yr) were used as controls. Subjects were submitted to a 8-week exercise-training program with cycle-ergometer for 1 h/day 3-4 days/week at 60% of their individual VO2 max. Before and after this period, resting venous serum osteocalcin and GH concentrations were measured in the same batch. The blood sampling after 8 weeks of the training program were performed after resting for one day. All patients and controls underwent also the following endocrine evaluation: serum cortisol, plasma ACTH.Our results demonstrate a significant increase of osteocalcin after physical exercise and a positive correlation between osteocalcin and GH. This later might suggest a role of GH in the increased osteocalcin secretion.The data of the present study suggest a positive effect of physical exercise on bone metabolism in patients with adrenal incidentaloma.

Diseases presenting "positive correlation" symptom

  • 22q11.2 deletion syndrome
  • acute rheumatic fever
  • adrenal incidentaloma
  • aromatase deficiency
  • congenital adrenal hyperplasia
  • congenital diaphragmatic hernia
  • cutaneous mastocytosis
  • dedifferentiated liposarcoma
  • familial mediterranean fever
  • hodgkin lymphoma, classical
  • inclusion body myositis
  • kallmann syndrome
  • legionellosis
  • oral submucous fibrosis
  • trochlear dysplasia
  • well-differentiated liposarcoma

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