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Genotype distribution of human papillomavirus in women with abnormal cervical cytology in an esophageal carcinoma high incidence area of China.
[esophageal carcinoma]
Infection
with
human
papillomavirus
(
HPV
)
could
affect
genesis
of
both
cervical
and
esophageal
cancers
.
The
type
-
specific
distribution
of
HPV
in
cervical
cytology
abnormalities
of
women
has
remained
unclear
in
Shantou
,
an
esophageal
cancer
high
-incidence
area
of
China
.
Data
from
22
,
617
women
who
were
subjected
to
cervical
HPV
DNA
testing
with
simultaneous
cervical
cytological
examination
during
2009
-
2013
were
therefore
here
retrospectively
evaluated
in
a
hospital-based
study
.
Overall
,
16
.
2
%
(
3
,
584
/
22
,
114
)
of
women
with
normal
cytology
were
HR
-HPV
positive
,
with
HPV-
52
(
4
.
07
%
)
as
the
most
common
type
followed
by
-
16
(
3
.
63
%
)
,
and
-
58
(
2
.
46
%
)
.
Prevalence
of
HR
-HPV
was
50
.
3
%
(
253
/
503
)
in
women
with
cervical
cytological
abnormalities
,
of
which
in
ASC
-H
71
.
4
%
,
ASC
-
US
39
.
1
%
,
HSIL
80
.
3
%
and
LSIL
73
.
7
%
.
HPV-
58
(
14
.
12
%
)
was
the
most
common
type
for
all
cervical
cytological
abnormalities
,
followed
by
HPV-
16
(
13
.
72
%
)
,
and
-
52
(
12
.
72
%
)
,
while
the
more
common
HPV-
16
type
in
ASC
-H
(
42
.
9
%
)
and
HSIL
(
36
.
1
%
)
,
HPV-
52
and
-
58
were
the
most
common
types
for
ASC
-
US
(
10
.
3
%
)
and
LSIL
(
25
%
)
,
respectively
.
Multiple
HPV
co
-infections
were
identified
in
33
.
2
%
(
84
/
253
)
cytology
abnormalities
with
positive
HR
-HPV
,
and
the
highest
prevalence
of
HPV-
58
/
16
combination
in
HSIL
(
28
.
6
%
,
6
/
21
)
was
observed
.
Our
data
indicated
a
relative
high
prevalence
of
HPV-
58
and
-
52
in
women
with
cervical
cytological
abnormalities
,
which
should
be
considered
in
the
development
of
next
-generation
vaccines
for
Shantou
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated
