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Lymphoepithelioma-like esophageal carcinoma with macroscopic reduction.
[esophageal carcinoma]
Esophageal
lymphoepithelioma-like
carcinoma
(
LELC
)
is
extremely
rare
.
We
report
the
first
case
of
esophageal
LELC
showing
macroscopic
reduction
.
A
67
-
year
-old
male
presented
with
dysphagia
and
,
by
endoscopic
examination
,
was
found
to
have
a
significantly
raised
tumor
of
10
mm
in
diameter
in
the
thoracic
esophagus
.
The
biopsied
material
showed
esophageal
cancer
.
We
performed
endoscopic
submucosal
dissection
.
However
,
the
tumor
became
flattened
,
similar
to
a
scar
,
in
only
2
mo
.
Histologically
,
the
carcinoma
cells
had
infiltrated
the
submucosal
layer
.
Prominent
infiltration
of
T
lymphoid
cells
that
stained
positive
for
CD
8
was
observed
around
the
carcinoma
cells
.
Therefore
,
this
lesion
was
considered
to
be
an
LELC
with
poorly
differentiated
squamous
cells
.
Because
the
margin
was
positive
,
an
esophagectomy
was
performed
.
Carcinoma
cells
were
detected
in
the
neck
in
one
lymph
node
.
The
staging
was
T
1
N
0
M
1
b
.
However
,
the
patient
has
been
well
,
without
adjuvant
therapy
or
recurrence
,
for
more
than
5
years
.
Diseases
Validation
Diseases presenting
"dysphagia"
symptom
alexander disease
cadasil
cushing syndrome
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
inclusion body myositis
kindler syndrome
liposarcoma
locked-in syndrome
neuralgic amyotrophy
oligodontia
triple a syndrome
well-differentiated liposarcoma
This symptom has already been validated