Rare Diseases Symptoms Automatic Extraction

Combined chemotherapy and surgery in primary small cell carcinoma of the esophagus.

[esophageal carcinoma]

The study was to retrospectively analyze survival outcomes of surgery combined with chemotherapy in primary small cell carcinoma of esophagus.From January 2000 to December 2009, all patients with esophageal carcinoma and underwent esophagectomy were selected from the Department of Thoracic Surgery, Henan Cancer Hospital, China. They were performed trans--left thoracic incision esophagectomy. For tumor located in the upper third thoracic esophagus, trans--right thoracic incision and abdomen incision esophagectomy was selected. We chose EP regimen for chemotherapy. Results: The percentage of pure esophagus small cell carcinoma (57 cases) in all patients underwent esophagectomy was 1.1%. The median survival time was 45 months. In stage I, II, III, the survival rate was 25%, 5.9%, 4.3% respectively. In the subgroup analysis, overall median survival time of surgery was 23.2 months while the time of combined surgery and chemotherapy was 60.7months (P＜0.01). For stage I patients, combined therapy was associated with a significant longer median survival time (81.9 months) than surgery alone (22.3months). (P＜0.01).Systemic chemotherapy of cisplatin--based regimens should be considered as important treatment options to improve survival outcome，even early small cell esophageal cancer.

Diseases presenting "cancer" symptom

  • achondroplasia
  • acute rheumatic fever
  • adrenal incidentaloma
  • alpha-thalassemia
  • benign recurrent intrahepatic cholestasis
  • cadasil
  • canavan disease
  • carcinoma of the gallbladder
  • cholangiocarcinoma
  • coats disease
  • congenital adrenal hyperplasia
  • congenital diaphragmatic hernia
  • cowden syndrome
  • cushing syndrome
  • cutaneous mastocytosis
  • dedifferentiated liposarcoma
  • dystrophic epidermolysis bullosa
  • epidermolysis bullosa simplex
  • erdheim-chester disease
  • erythropoietic protoporphyria
  • esophageal adenocarcinoma
  • esophageal carcinoma
  • esophageal squamous cell carcinoma
  • familial hypocalciuric hypercalcemia
  • familial mediterranean fever
  • gm1 gangliosidosis
  • heparin-induced thrombocytopenia
  • hereditary cerebral hemorrhage with amyloidosis
  • hirschsprung disease
  • hodgkin lymphoma, classical
  • inclusion body myositis
  • junctional epidermolysis bullosa
  • kabuki syndrome
  • kallmann syndrome
  • kindler syndrome
  • lamellar ichthyosis
  • liposarcoma
  • locked-in syndrome
  • lymphangioleiomyomatosis
  • monosomy 21
  • neuralgic amyotrophy
  • oculocutaneous albinism
  • oligodontia
  • oral submucous fibrosis
  • papillon-lefèvre syndrome
  • pendred syndrome
  • pleomorphic liposarcoma
  • primary effusion lymphoma
  • proteus syndrome
  • pyomyositis
  • pyruvate dehydrogenase deficiency
  • severe combined immunodeficiency
  • sneddon syndrome
  • systemic capillary leak syndrome
  • triple a syndrome
  • von hippel-lindau disease
  • waldenström macroglobulinemia
  • well-differentiated liposarcoma
  • werner syndrome
  • wiskott-aldrich syndrome
  • wolf-hirschhorn syndrome
  • x-linked adrenoleukodystrophy

This symptom has already been validated