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[Obesity and cancer: «Dangerous friendship»]
[esophageal adenocarcinoma]
Obesity
and
cancer
are
one
of
the
most
important
health
problems
is
Spain
.
Between
23
and
28
%
of
the
adult
population
in
Spain
are
obese
,
39
%
are
overweight
and
36
%
have
abdominal
obesity
.
The
association
between
obesity
and
type
2
diabetes
mellitus
,
hypertension
,
dyslipidemia
and
sleep
obstructive
apnea
is
well
known
.
On
the
contrary
,
the
association
between
obesity
and
cancer
is
less
known
,
because
the
recent
evidence
on
it
.
Several
prospective
studies
have
shown
during
the
last
years
the
strong
relationship
between
obesity
and
cancer
of
colon
,
breast
in
post-menopausal
women
,
endometrial
,
kidney
and
pancreas
as
well
as
esophageal
adenocarcinoma
.
Furthermore
there
is
recent
evidence
showing
that
liver
,
gallbladder
,
thyroid
and
ovarian
cancer
as
well
as
leukemia
,
multiple
myeloma
and
Hodgkin
lymphomas
are
probably
associated
with
obesity
,
yet
more
studies
are
needed
.
A
better
knowledge
of
the
relation
between
cancer
and
obesity
will
allow
improving
the
prevention
strategies
against
cancer
,
a
more
efficient
early
detection
,
and
a
more
suitable
treatment
of
obesity
and
overweight
.
Although
the
mechanisms
of
carcinogenesis
of
obesity
are
not
well
established
,
avoiding
overweight
and
obesity
are
considered
one
of
the
best
approaches
to
reduce
the
risk
of
cancer
.
Therefore
the
general
population
must
be
aware
that
cancer
is
one
of
the
most
important
hazards
associated
with
the
current
obesity
epidemic
in
our
society
.
Diseases
Validation
Diseases presenting
"hypertension"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
aniridia
aromatase deficiency
cadasil
child syndrome
cohen syndrome
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cushing syndrome
cystinuria
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
fabry disease
familial hypocalciuric hypercalcemia
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
holt-oram syndrome
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
inclusion body myositis
kallmann syndrome
kindler syndrome
lamellar ichthyosis
lymphangioleiomyomatosis
pendred syndrome
primary effusion lymphoma
scrub typhus
severe combined immunodeficiency
sneddon syndrome
typhoid
von hippel-lindau disease
well-differentiated liposarcoma
werner syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
This symptom has already been validated