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[Obesity and cancer: «Dangerous friendship»]
[esophageal adenocarcinoma]
Obesity
and
cancer
are
one
of
the
most
important
health
problems
is
Spain
.
Between
23
and
28
%
of
the
adult
population
in
Spain
are
obese
,
39
%
are
overweight
and
36
%
have
abdominal
obesity
.
The
association
between
obesity
and
type
2
diabetes
mellitus
,
hypertension
,
dyslipidemia
and
sleep
obstructive
apnea
is
well
known
.
On
the
contrary
,
the
association
between
obesity
and
cancer
is
less
known
,
because
the
recent
evidence
on
it
.
Several
prospective
studies
have
shown
during
the
last
years
the
strong
relationship
between
obesity
and
cancer
of
colon
,
breast
in
post-menopausal
women
,
endometrial
,
kidney
and
pancreas
as
well
as
esophageal
adenocarcinoma
.
Furthermore
there
is
recent
evidence
showing
that
liver
,
gallbladder
,
thyroid
and
ovarian
cancer
as
well
as
leukemia
,
multiple
myeloma
and
Hodgkin
lymphomas
are
probably
associated
with
obesity
,
yet
more
studies
are
needed
.
A
better
knowledge
of
the
relation
between
cancer
and
obesity
will
allow
improving
the
prevention
strategies
against
cancer
,
a
more
efficient
early
detection
,
and
a
more
suitable
treatment
of
obesity
and
overweight
.
Although
the
mechanisms
of
carcinogenesis
of
obesity
are
not
well
established
,
avoiding
overweight
and
obesity
are
considered
one
of
the
best
approaches
to
reduce
the
risk
of
cancer
.
Therefore
the
general
population
must
be
aware
that
cancer
is
one
of
the
most
important
hazards
associated
with
the
current
obesity
epidemic
in
our
society
.
Diseases
Validation
Diseases presenting
"efficient early detection"
symptom
esophageal adenocarcinoma
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