Esophageal adenocarcinoma with white opaque substance observed by magnifying endoscopy with narrow band imaging.

[esophageal adenocarcinoma]

White opaque substance (WOS ) is observed in the gastric neoplasia of 0 -IIa type using magnifying endoscopy with narrow band imaging (NBI-ME ). Colonic and duodenal neoplasms with WOS have also been reported . Immunohistochemical examination with adipophilin reveals WOS in gastric neoplasms as lipid droplets , and WOS is specific for neoplasm with intestinal or gastrointestinal phenotype . We herein report a case of adenocarcinoma of the esophagogastric junction with WOS . A male patient in his sixties was found by esophagogastroduodenoscopy to have an esophageal elevated lesion . NBI-ME showed whitish deposits that looked similar to WOS in gastric neoplasms . The patient underwent endoscopic submucosal dissection and the lesion was resected in a single piece . This tumor had diffuse positivity for adipophilin and gastrointestinal phenotype .