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[Etiologies of 1 173 hospitalized cases with adrenal incidentaloma].
[adrenal incidentaloma]
To
summarize
the
characteristics
of
etiological
distribution
of
adrenal
incidentaloma
during
the
past
20
years
.
All
the
relevant
data
of
adrenal
incidentaloma
patients
admitted
into
Chinese
PLA
General
Hospital
between
January
1993
and
January
2013
were
collected
.
Their
gender
ratio
,
visiting
ages
and
final
diagnoses
were
retrospectively
analyzed
.
There
were
1
173
patients
were
collected
,
of
which
,
629
(
53
.
62
%
)
males
and
544
(
46
.
38
%
)
females
with
a
mean
age
of
(
50
.
84
±
12
.
13
)
years
.
There
were
669
(
57
.
03
%
)
hypertensive
cases
and
622
cases
undergone
adrenalectomy
.
Routine
medical
checkup
and
abdominal
discomfort
led
to
the
discovery
of
adrenal
incidentalomas
.
As
to
the
etiologies
,
there
were
non-
functional
tumors
(
n
=
809
,
68
.
97
%
)
,
pheochromocytoma
(
n
=
137
,
11
.
68
%
)
,
primary
aldosteronism
(
n
=
84
,
7
.
16
%
)
and
adrenal
Cushing
syndrome
(
n
=
65
,
5
.
54
%
)
.
The
proportions
of
adrenal
cortical
carcinomas
and
metastases
were
1
.
70
%
(
n
=
20
)
and
1
.
36
%
(
n
=
16
)
respectively
.
Compared
with
normotension
group
,
the
proportion
of
non-
functional
lesions
in
hypertension
group
was
significant
lower
(
73
.
81
%
vs
65
.
32
%
,
P
<
0
.
05
)
while
the
proportions
of
primary
aldosteronism
and
adrenal
Cushing
syndrome
were
higher
(
11
.
96
%
vs
0
.
79
%
,
5
.
83
%
vs
5
.
18
%
,
both
P
<
0
.
05
)
.
Adrenal
incidentaloma
patients
with
concurrent
hypentension
is
quite
common
.
In
respect
of
etiologies
,
non-
functional
tumor
is
the
most
common
and
followed
by
pheochromocytoma
and
primary
aldosteronism
Cushing
syndrome
.
Diseases
Validation
Diseases presenting
"hypertension"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
aniridia
aromatase deficiency
cadasil
child syndrome
cohen syndrome
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cushing syndrome
cystinuria
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
fabry disease
familial hypocalciuric hypercalcemia
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
holt-oram syndrome
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
inclusion body myositis
kallmann syndrome
kindler syndrome
lamellar ichthyosis
lymphangioleiomyomatosis
pendred syndrome
primary effusion lymphoma
scrub typhus
severe combined immunodeficiency
sneddon syndrome
typhoid
von hippel-lindau disease
well-differentiated liposarcoma
werner syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
This symptom has already been validated