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The peculiar epidemiology of dracunculiasis in Chad.
[dracunculiasis]
Dracunculiasis
was
rediscovered
in
Chad
in
2010
after
an
apparent
absence
of
10
years
.
In
April
2012
active
village
-based
surveillance
was
initiated
to
determine
where
,
when
,
and
how
transmission
of
the
disease
was
occurring
,
and
to
implement
interventions
to
interrupt
it
.
The
current
epidemiologic
pattern
of
the
disease
in
Chad
is
unlike
that
seen
previously
in
Chad
or
other
endemic
countries
,
i
.
e
.
,
no
clustering
of
cases
by
village
or
association
with
a
common
water
source
,
the
average
number
of
worms
per
person
was
small
,
and
a
large
number
of
dogs
were
found
to
be
infected
.
Molecular
sequencing
suggests
these
infections
were
all
caused
by
Dracunculus
medinensis
.
It
appears
that
the
infection
in
dogs
is
serving
as
the
major
driving
force
sustaining
transmission
in
Chad
,
that
an
aberrant
life
cycle
involving
a
paratenic
host
common
to
people
and
dogs
is
occurring
,
and
that
the
cases
in
humans
are
sporadic
and
incidental
.
Diseases
Validation
Diseases presenting
"large number"
symptom
acute rheumatic fever
adrenal incidentaloma
allergic bronchopulmonary aspergillosis
canavan disease
coats disease
cowden syndrome
dedifferentiated liposarcoma
dracunculiasis
epidermolysis bullosa simplex
fabry disease
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
kindler syndrome
legionellosis
malignant atrophic papulosis
neuralgic amyotrophy
phenylketonuria
pleomorphic liposarcoma
primary effusion lymphoma
scrub typhus
severe combined immunodeficiency
triple a syndrome
waldenström macroglobulinemia
well-differentiated liposarcoma
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
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