Rare Diseases Symptoms Automatic Extraction
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A national prospective surveillance study of acute rheumatic fever in Australian children.
[acute rheumatic fever]
Acute
rheumatic
fever
(
ARF
)
is
an
important
cause
of
heart
disease
in
Indigenous
people
of
northern
and
central
Australia
.
However
,
little
is
known
about
ARF
in
children
across
all
Australian
population
groups
.
This
national
prospective
study
was
conducted
to
determine
patterns
of
disease
,
and
populations
and
regions
at
highest
risk
.
The
Australian
Paediatric
Surveillance
Unit
surveillance
model
was
used
to
collect
data
on
children
with
ARF
across
Australia
.
Children
up
to
15
years
of
age
were
included
if
they
had
an
ARF
episode
diagnosed
between
October
1
,
2007
and
December
31
,
2010
that
met
the
case
definition
.
ARF
was
identified
in
151
children
:
131
Indigenous
Australians
,
10
non-
Indigenous
Australians
,
8
Pacific
Islanders
and
1
African
(
1
unknown
)
.
Common
presenting
features
were
joint
symptoms
,
fever
and
carditis
.
Sydenham
chorea
was
reported
in
19
%
of
children
.
Aseptic
monoarthritis
was
a
major
manifestation
in
19
%
of
high
-risk
children
.
Seven
non-
Indigenous
Australian
children
presented
with
classic
,
highly
specific
features
compared
with
23
%
of
high
-risk
children
,
suggesting
that
subtle
presentations
of
ARF
are
being
missed
in
non-
Indigenous
children
.
Recent
sore
throat
was
reported
in
33
%
of
cases
,
including
25
%
of
remote
Indigenous
children
.
There
were
delays
in
presentation
to
care
and
referral
to
higher-level
care
across
urban
/
rural
and
remote
areas
.
ARF
may
be
more
common
than
previously
thought
among
low
-risk
children
.
These
data
should
prompt
an
awareness
of
ARF
diagnosis
and
management
across
all
regions
,
including
strategies
for
primary
prevention
.
There
should
be
renewed
emphasis
on
treatment
of
sore
throat
in
high
-risk
groups
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated