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Genomic investigation of dedifferentiated liposarcoma suggests a role for therapeutic targeting of the tumor epigenome.
[dedifferentiated liposarcoma]
A
comprehensive
genetic
analysis
of
dedifferentiated
liposarcomas
suggests
that
epigenetic
modifications
are
common
and
may
alter
the
differentiation
capacity
in
these
tumors
.
Furthermore
,
these
data
suggest
that
treatment
strategies
aimed
at
altering
histone
acetylation
and
/
or
DNA
methylation
are
worthy
of
further
study
.
