Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Impact of a metabolic stone clinic on management of patients with cystinuria: 5 years follow-up.
[cystinuria]
Cystinuric
patients
develop
new
stones
and
exhibit
stone
growth
despite
conservative
measures
and
often
require
surgical
intervention
.
There
have
been
reports
of
better
outcome
both
in
surgical
intervention
rates
and
compliance
when
patients
were
referred
to
dedicated
metabolic
stone
clinics
.
We
wish
to
report
our
experience
in
the
running
of
a
metabolic
stone
disease
clinic
and
to
compare
our
intervention
rates
to
the
pre-metabolic
stone
clinic
period
in
our
department
.
We
reviewed
retrospectively
our
cystinuria
patients
'
database
between
the
years
of
1992
and
2008
.
Patients
were
divided
into
two
groups
.
Group
A
patients
(
n
=
28
)
were
treated
before
the
introduction
of
a
dedicated
stone
clinic
(
years
1992
-
2002
)
and
group
B
patients
(
n
=
28
)
after
the
establishment
of
the
metabolic
stone
clinic
but
every
group
B
patient
had
a
minimum
follow
up
of
5
years
.
21
patients
were
common
between
the
two
groups
.
Main
therapy
included
hyperdiuresis
and
alkalization
.
Parameters
recorded
included
the
number
of
clinic
visits
,
whether
the
patients
were
stone
free
or
asymptomatic
at
the
time
of
our
review
and
the
nature
and
frequency
of
surgical
intervention
.
A
total
number
of
145
procedures
were
carried
out
in
group
A
including
89
ESWL
,
27
PCNL
,
24
ureteroscopy
retrograde
lithotripsies
and
5
open
procedures
.
In
group
B
,
a
total
of
54
procedures
were
carried
out
and
included
6
ESWL
,
5
PCNL
and
43
ureteroscopy
laser
lithotripsies
.
The
average
number
of
surgical
interventions
per
patient
per
year
was
0
.
74
and
0
.
34
in
group
A
and
B
respectively
.
The
number
of
clinic
attendances
increased
in
group
B
to
279
from
188
in
group
A
.
Stone
free
rates
were
46
%
for
group
A
and
50
%
for
group
B
patients
but
all
group
B
patients
were
asymptomatic
at
the
time
of
our
review
.
The
introduction
of
a
dedicated
cystinuria
clinic
halved
the
intervention
rate
in
this
complicated
group
of
patients
.
The
majority
of
surgical
procedures
shifted
towards
ureteroscopies
(
both
as
inpatients
and
as
day
case
procedures
)
.
We
believe
that
cystine
stone
patients
should
be
managed
in
a
devoted
metabolic
stone
clinic
.
With
this
approach
,
compliance
is
better
achieved
and
surgical
intervention
is
less
,
resulting
in
better
clinical
outcome
,
and
less
burden
both
for
the
patient
and
the
urological
services
.
Diseases
Validation
Diseases presenting
"dedicated cystinuria clinic halved the intervention rate in this complicated group"
symptom
cystinuria
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom