Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Multicentric mast cell tumors in a horse.
[cutaneous mastocytosis]
A
6
-
year
-old
female
Rocky
Mountain
horse
was
presented
for
evaluation
of
draining
tracts
and
distal
limb
subcutaneous
edema
on
the
left
front
and
left
hind
limbs
that
had
been
present
for
2
weeks
.
Direct
smears
of
fluid
collected
by
fine-needle
aspiration
of
subcutaneous
fluid
from
both
limbs
were
highly
cellular
with
a
predominance
of
eosinophils
accompanied
by
numerous
,
moderately
atypical
,
variably
granulated
mast
cells
.
The
cytologic
diagnosis
was
mast
cell
tumor
(
MCT
)
with
prominent
eosinophilic
infiltration
with
a
differential
diagnosis
of
eosinophilic
granuloma
.
Histologic
evaluation
of
surgical
biopsies
of
lesions
from
both
limbs
was
performed
on
sections
stained
with
H
&
E
,
toluidine
blue
,
and
Luna
stains
.
The
histologic
diagnosis
was
MCT
,
and
staining
with
toluidine
blue
and
Luna
stains
confirmed
the
presence
of
mast
cells
and
eosinophils
,
respectively
.
In
addition
,
the
mast
cells
strongly
expressed
CD
117
.
This
is
the
first
reported
case
of
cutaneous
mast
cell
neoplasia
in
a
horse
in
which
primary
presenting
complaints
were
draining
tracts
and
distal
limb
subcutaneous
edema
involving
multiple
limbs
.
This
case
illustrates
the
utility
of
staining
for
CD
117
expression
in
combination
with
traditional
stains
,
such
as
toluidine
blue
and
Luna
,
in
differentiating
MCTs
from
other
eosinophilic
lesions
in
horses
.
