Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Bullous mastocytosis in infancy: a rare presentation].
[cutaneous mastocytosis]
Mastocytosis
is
a
rare
condition
related
to
an
abnormal
proliferation
of
mast
cells
and
their
accumulation
in
tissues
.
Cutaneous
mastocytosis
is
the
most
common
form
and
mainly
affects
newborns
and
infants
.
The
symptoms
are
caused
by
the
release
of
mediators
contained
in
mast
cells
,
including
histamine
.
Mastocytosis
may
be
associated
with
a
mutation
in
the
gene
encoding
the
c-kit
receptor
.
Clinically
,
there
are
different
dermatological
findings
,
which
combine
acute
cutaneous
,
digestive
,
or
even
hemodynamic
manifestations
in
varying
degrees
.
The
diagnosis
is
confirmed
by
the
histological
study
of
a
skin
sample
.
We
report
here
the
case
of
a
4
-
month
-old
infant
suffering
from
diffuse
cutaneous
bullous
mastocytosis
,
a
very
rare
variety
of
mastocytosis
.
This
infant
had
an
erosive
and
bullous
manifestation
of
dermatosis
,
initially
confused
with
impetigo
.
The
proliferation
of
bullous
lesions
led
to
her
hospitalization
.
Codeine
intake
for
pain
was
responsible
for
a
large
and
extensive
bullous
reaction
associated
with
anaphylactic
shock
.
This
context
of
bullous
spread
occurring
after
taking
codeine
led
to
the
suspicion
of
bullous
diffuse
cutaneous
mastocytosis
,
a
diagnosis
that
was
confirmed
histologically
.
This
observation
demonstrates
the
difficulty
of
mastocytosis
diagnosis
,
mostly
due
to
its
rarity
,
especially
in
its
diffuse
bullous
forms
.
The
rapid
deterioration
of
this
patient
,
after
the
codeine
prescription
,
emphasizes
the
importance
of
the
eviction
of
histamine-releaser
compounds
in
the
management
of
this
disease
.
Diseases
Validation
Diseases presenting
"common form"
symptom
achondroplasia
alexander disease
benign recurrent intrahepatic cholestasis
cadasil
child syndrome
classical phenylketonuria
cutaneous mastocytosis
erythropoietic protoporphyria
familial mediterranean fever
hereditary cerebral hemorrhage with amyloidosis
hodgkin lymphoma, classical
holt-oram syndrome
homocystinuria without methylmalonic aciduria
oral submucous fibrosis
pendred syndrome
primary hyperoxaluria type 1
severe combined immunodeficiency
thoracic outlet syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom