Unusual triad of obstructive sleep apnea, uncontrolled hypertension, and severe hypokalemia due to ectopic adrenocorticotropic secretion.

[cushing syndrome]

Ectopic adrenocorticotropic hormone secretion is responsible for 12 % to 17 % of all cases of the Cushing syndrome . One of the most commonly described causes of ectopic adrenocorticotropic hormone secretion is small cell carcinoma of the lung . A rare cause includes a functioning neuroendocrine tumor traditionally known as carcinoids that account for 5 % of all mediastinal tumors . To our knowledge , all reported cases of mediastinal carcinoids are thymic in origin and only a minority of those is functional . We present a male patient with hypertension , obstructive sleep apnea , and acid-base disorder , in whom further investigation revealed an anterior mediastinal mass and Cushing syndrome .

Diseases
Validation

Diseases presenting "hypertension" symptom

achondroplasia

acute rheumatic fever

adrenal incidentaloma

aniridia

aromatase deficiency

cadasil

child syndrome

cohen syndrome

congenital adrenal hyperplasia

congenital diaphragmatic hernia

cushing syndrome

cystinuria

erdheim-chester disease

erythropoietic protoporphyria

esophageal adenocarcinoma

fabry disease

familial hypocalciuric hypercalcemia

gm1 gangliosidosis

heparin-induced thrombocytopenia

hereditary cerebral hemorrhage with amyloidosis

holt-oram syndrome

homocystinuria without methylmalonic aciduria

hydrocephalus with stenosis of the aqueduct of sylvius

inclusion body myositis

kallmann syndrome

kindler syndrome

lamellar ichthyosis

lymphangioleiomyomatosis

pendred syndrome

primary effusion lymphoma

scrub typhus

severe combined immunodeficiency

sneddon syndrome

typhoid

von hippel-lindau disease

well-differentiated liposarcoma

werner syndrome

x-linked adrenoleukodystrophy

zellweger syndrome

This symptom has already been validated