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Exogenous Cushing Syndrome: A Lesson of Diaper Rash Cream.
[cushing syndrome]
A
prolonged
use
of
topical
corticosteroids
can
result
in
Cushing
syndrome
,
though
this
is
less
common
than
with
oral
or
parenteral
steroids
.
Most
pediatric
cases
were
due
to
application
of
topical
steroids
for
diaper
dermatitis
.
Adverse
cardiovascular
effects
can
occur
in
Cushing
syndrome
with
significant
long
-term
morbidity
and
mortality
,
though
so
far
there
have
been
no
reports
of
cardiovascular
complications
due
to
excessive
usage
of
topical
steroids
.
We
report
a
2
.
5
-
month
-old
boy
who
rapidly
developed
severe
Cushing
syndrome
induced
by
the
misuse
of
topical
clobetasol
,
a
very
potent
steroid
,
without
a
doctor
's
prescription
as
a
diaper
rash
cream
,
and
developed
moderate
left
ventricular
hypertrophy
and
pericardial
effusion
.
©
2014
S
.
Karger
AG
,
Basel
.
Diseases
Validation
Diseases presenting
"mortality"
symptom
congenital diaphragmatic hernia
cushing syndrome
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
heparin-induced thrombocytopenia
junctional epidermolysis bullosa
lamellar ichthyosis
legionellosis
locked-in syndrome
megacystis-microcolon-intestinal hypoperistalsis syndrome
oculocutaneous albinism
scrub typhus
systemic capillary leak syndrome
thoracic outlet syndrome
typhoid
von hippel-lindau disease
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