Coexisting atypical polypoid adenomyoma and endometrioid endometrial carcinoma in a young woman with Cowden Syndrome: Case report and implications for screening and prevention.

[cowden syndrome]

► Cowden Syndrome is a rare hereditary cancer syndrome , which confers an increased risk of breast , thyroid , endometrial and colon cancer . ► Atypical polypoid adenomyoma does not generally represent a premalignant lesion , but must be carefully screened for foci of malignancy . ► Cancer screening must be intensified for patients who meet the diagnostic criteria for Cowden Syndrome .